New methods in the treatment of benign and malignant neoplasms of the cervical-cephalic region by surgical ablation and reconstruction with local and distant flaps in combination with new chemo- and radiotherapy protocols.

This line of research was also supported by a three-year scholarship made available by AIRC (Italian Association for Cancer Research) and the results have resulted in the following publications:

1) Brusati R., Bozzetti A., Chiapasco M.: Facial nerve and parotid surgery. Journal Maxillofacial Surgery1987: (5) 15: 278-280

2) Contini S., Consigli GF., Di Lecce F., Casalini A., Chiapasco M., Ferrari G.: A panendoscopic approach with vital staining for tumors of the upper aerodigestive tract. Gastrointestinal endoscopy 1988: 34 (3): 283

3) Brusati R., Collini M., Bozzetti A., Chiapasco M., Galioto S.: The pectoralis major musculo-cutaneous flap: our experience in 100 cases. Journal Cranio-Maxillo-Facial Surgery 1988: 16: 35-39
Contini S, Consigli GF, Di Lecce F, Chiapasco M, Ferri M, Orsi P: Vital staining of oesophagus in patients with head and neck cancer: still a worthwhile procedure. Italian Journal of Gastroenterology 1991: 23(1); 5-8

New surgical methods in the management of cleft lip and palate outcomes.

The results have been published in the following publications:

1) Ronchi P., Chiapasco M.: Endosseous implants for prosthetic rehabilitation in bone grafted alveolar clefts. Journal Cranio-Maxillo-Facial Surgery 1995: 23: 382-386 Chiapasco M: Use of endosseous implants for dental reconstruction of patients with grafted alveolar clefts. Journal Oral & Maxillofacial Surgery 1997: 55:6: 584 Chiapasco M: Reconstruction of residual alveolar cleft defects with one-stage mandibular bone grafts and osseointegrated implants. Journal Oral & Maxillofacial Surgery 1998: 56: 467

New methods in the reconstruction of the atrophic posterior maxilla for implant purposes.

In this field he is the coordinator of a multicenter clinical study supported by Straumann Institute (Basel – Switzerland) entitled: “Maxillary sinus grafting with Bio-Oss® or Straumann® Bone Ceramic followed by delayed placement of Straumann® dental implants: A comparative histomorphometric and clinical study”. The results have been included in the following publications:

1) Chiapasco M, Ronchi P: Sinus lift and endosseous implants: Preliminary surgical and prosthetic results. European Journal Prosthodontics & Restorative Dentistry 1994: 3 (1):15-21 Chiapasco M., Ronchi P.: Sinus lift and endosseous implants. Journal Cranio-maxillofacial Surgery 1994 :22 suppl 1: 73-74 Chiapasco M, Zaniboni M, Rimondini L: Dental Implants placed in grafted maxillary sinuses: a retrospective analysis of clinical outcome according to the initial clinical situation and a proposal of defect classification. Clinical oral Implants Research 2008:19:416-428 Cordaro L, Bosshardt DD, Palatella PM, Rao W, Serino G, Chiapasco M. Maxillary sinus grafting with Bio-oss® or Straumann® Bone Ceramic: histomorphometric results from a randomized controlled multicenter clinical trial. Clinical Oral Implants Research 2008: 19: 796-803 Chiapasco M, Zaniboni M: Methods to treat the edentulous posterior maxilla: Implants with sinus grafting. Journal Oral & Maxillofacial Surgery 2009: 67: 867-871.

New methods in the reconstruction of atrophic jaws for implantological purposes using bone grafts or regenerative techniques with biomaterials.

The results were included in the following publications:

1) Chiapasco M, Romeo E, Abati S.: A comparative study between guided bone regeneration and autologous bone blocks for the reconstruction of narrow edentulous ridges. Journal Clinical Periodontology 1997: 24 (11): 870

2) Chiapasco M, Romeo E, Vogel G: Three-dimensional reconstruction of knife-edge edentulous maxillae by sinus lift, onlay grafts and sagittal osteotomy of the anterior maxilla: Preliminary surgical and prosthetic results.International Journal of Oral & Maxillofacial Implants 1998: 13: 394-399

3) Chiapasco M., Abati S., Romeo E., Vogel G.: Clinical outcome of autogenous bone blocks or guided bone regeneration with e-PTFE membranes for the reconstruction of narrow edentulous ridges. Clinical Oral Implants Research 1999: 10; 278-288

4) Chiapasco M, Ferrini F, Casentini P, Accardi S, Zaniboni M: Dental implants placed in expanded narrow edentulous ridges with the Extension-Crest® device: a 1- to 3-year multicenter follow-up study. Clinical Oral Implants Research 2006: 17: 265-272 Chiapasco M, Zaniboni M, Boisco M: EAO: Augmentation procedures for the rehabilitation of deficient edentulous ridges with oral implants: Clinical Oral Implants Research 2006: 17 (suppl .2) 136-159.

5) Chiapasco M, Brusati R, Ronchi P: Le Fort I osteotomy with interpositional bone grafts and delayed dental implants for the rehabilitation of extremely atrophied maxillae: a 1 to 9-year clinical follow-up study on humans. Clinical Oral Implants Research 2007: 18: 74-85

6) Chiapasco M, Zaniboni M: Clinical outcome of GBR procedure to correct peri-implant dehiscences and fenestrations: a systematic review. Clinical Oral Implants research 2009: 20 (suppl 4) 113-123.

7) Chiapasco M, Casentini P, Zaniboni M: Bone augmentation procedures in implant dentistry. International Journal Oral & Maxillofacial Implants 2009: 24 (suppl) 237-259

8) Chen S, Beagle J, Jensen SS, Chiapasco M, Darby I: Consensus statement and recommended clinical procedures regarding surgical techniques. International Journal of Oral and maxillofacial Implants 2009: 24 (supplement) 272-278

9) Chiapasco M, Autelitano L, Rabbiosi D, Zaniboni M. The role of pericranium grafts in the reduction of post-operative dehiscences and bone resorption after reconstruction of severely deficient edentulous ridges with autogenous onlay bone grafts.
Chiapasco M, Casentini P, Zaniboni M. Implants in reconstructed bone: a comparative study on the outcome of Straumann® Tissue Level and Bone Level implants placed in vertically deficient alveolar ridges treated by means of autogenous onlay bone grafts. Clinical Implant Dentistry and Related Research (early view – electronic issue).

New methods on loading times of endosseous implants for prosthetic purposes

The results have been published in the following publications:

1) Chiapasco M, C. Gatti, Rossi E., Markwalder T., W. Hafliger: Implant-retained mandibular overdentures with immediate loading: A retrospective study on 226 consecutive cases. Clinical Oral Implants Research 8: 1997: 48-57

2) Gatti C., Haefliger W., Chiapasco M.: Implant-retained mandibular overdentures with immediate loading: a prospective study of ITI implants. International Journal Oral Maxillofacial Implants 2000: 15: 383-388

3) Chiapasco M., Abati S., Romeo E., Vogel G.: Implant-retained mandibular overdentures with Brånemark system MKII implants: A prospective comparative study between delayed and immediate loading. International Journal Oral Maxillofacial Implants 2001: 16 (4): 537-546

4) Romeo E., Chiapasco M., Lazza A., Casentini P., Ghisolfi M., Iorio M., Vogel G.: Implant-retained mandibular overdentures with ITI oral implants: A comparison of 2-year results between delayed and immediate loading. Clinical Oral Implants Research 2002:13: 495-501

5) Gatti C., Chiapasco M.: Immediate loading of Branemark implants: a 24-month follow-up of a comparative prospective pilot study between mandibular overdentures supported by Conical® transmucosal implants and standard MK II implants. Clinical Implant Dentistry and Related Research 2002: 4: 190-199:

6) Chiapasco M., Gatti C.: Implant-retained mandibular overdentures with immediate loading: a 3 to 8-year prospective study on 328 implants. Clinical Implant Dentistry and Related Research 2003: 5:1:29-39

7) Chiapasco, M., Gatti, C. Immediate loading of dental implants placed in revascularized fibula free flaps: a clinical report on 2 consecutive patients. International Journal Oral Maxillofacial Implants 2004: 19:906-912

8) Chiapasco, Gatti C, Gatti F: Immediate loading of dental implants placed in severely resorbed edentulous mandibles reconstructed with autogenous calvarial grafts. Clinical Oral Implants Research 2007:18: 13-20

New methods of bone regeneration by osteogenetic distraction

The results have been published in the following publications:

1) Chiapasco M., Brusati R., Galioto S.: Distraction osteogenesis of a fibular revascularized flap for improvement of oral implants positioning in a tumor patient: a case report. Journal Oral Maxillofacial Surgery 2000: 58: 1434-1439

2) Chiapasco M., Romeo E, Vogel G.: Vertical Distraction osteogenesis of edentulous ridges for improvement of oral implant positioning: A clinical report of preliminary results. International Journal of Oral and Maxillofacial Implants 2001: 16:43-51

3) Chiapasco M., Romeo E., Casentini P., Rimondini L: Alveolar distraction osteogenesis vs. vertical guided bone regeneration for the correction of vertically deficient edentulous ridges: a 1-3-year prospective study on humans. Clinical Oral Implants Research 2004: 15; 82-95
Chiapasco M, Consolo U, Bianchi A, Ronchi P. Alveolar distraction osteogenesis for the correction of vertically deficient edentulous ridges: a multicenter prospective study on humans. International Journal of oral and Maxillofacial Implants 2004 :19; 399-407
Chiapasco M, Lang NP, Bosshardt DD: Quality and Quantity of Bone following Alveolar Distraction Osteogenesis in the Human Mandible. Clinical Oral Implants Research 2006: 17: 394-402
Chiapasco M, Zaniboni M, Rimondini L: Autogenous onlay bone grafts vs alveolar distraction osteogenesis for the correction of vertically deficient edentulous ridges: a 2-4 year prospective study on humans. Clinical Oral Implants Research 2007:18; 432-440

New rehabilitation techniques for patients undergoing destructive surgery for tumors and reconstructive surgery through bone transplants and dental implants

The results have been published in the following publications:

1) Chiapasco M., Abati S., Ramundo G., Rossi A., Romeo E., Vogel G.: Behavior of implants in bone grafts or free flaps after tumor resection. Clinical Oral Implants Research 2000:11: 66-75 Chiapasco M.: Implants for patients with maxillofacial defects and following irradiation. Proceedings III European Workshop on Periodontology.Edited by: NL Lang, T. Karring, J. Lindhe: Quintessence Books; Quintessenz Verlags-GmbH, Berlin, 1999: 557-607 Chiapasco M, Biglioli F, Autelitano L, Romeo E, Brusati R: Clinical outcome of dental implants placed in fibula-free flaps used for the reconstruction of maxillo-mandibular defects following ablation for tumors or osteoradionecrosis. Clinical Oral Implants Research 2006: 17: 220-228 Chiapasco M, Colletti G, Romeo E, Zaniboni M, Brusati R: Long-term results of mandibular reconstruction with autogenous bone grafts and oral implants after tumor resection. Clinical oral Implants Research 2008:19; 1074-108

New guided and/or protected bone regeneration methods using customized titanium grids in the presence of severe atrophy of edentulous jaws

1) Chiapasco M, Casentini P, Tommasato G, Dellavia C, Del Fabbro M. Customized CAD/CAM titanium meshes for the guided bone regeneration of severe alveolar ridge defects: Preliminary results of a retrospective clinical study in humans. Clin Oral Impl Res.2021;00:1–13.https://doi.org/10.1111/clr.13720

2) Chiapasco M, Tommasato G, Del Fabbro M, et al. Customized CAD/CAM titanium meshes for protected bone regeneration of severe alveolar ridge defects: A comparative study between non-occlusive and semiocclusive meshes. Preliminary results of a prospective clinical study in humans (in preparation)

The application of digital workflow for the planning and implementation of regenerative interventions of bone and oral soft tissues

Tommasato, G., Piano, S., Casentini, P., De Stavola, L., & Chiapasco, M. (2024). Digital planning and bone regenerative technologies: A narrative review. Clinical Oral Implants Research, 35, 906–921.

New methods for minimizing surgical invasiveness in reconstructive and regenerative techniques

1) Urban I, Montero E, Sanz I, David Palombo, Monje A, Tommasato G, Matteo Chiapasco. Minimal invasiveness in vertical ridge augmentation. Periodontology 2000. 2022;00:1-19. doi:10.1111/prd.12479

2) Testori T, Clauser T, Rapani A, Artzi Z, Avila-Ortiz G, Barootchi S, Bressan E, Chiapasco M., et al.  Indications for implant-supported rehabilitation of the posterior atrophic maxilla: A multidisciplinary consensus among experts in the field utilizing the Modified Delphi method.  Int J Oral Implantol 2024: 17(1): 89-100

The multidisciplinary oro-maxillofacial, ENT, and medical approach to infections of the facial massif/paranasal sinuses

1) Chiapasco M, Tommasato G. Management of Oral Surgery-Related Complications. Otolaryngologic Clinics  North  America  2024 (vol. 57:6) 1139-1156

2) Chiapasco M, Tommasato G, Saibene A, Craig J. A multidisciplinary approach to odontogenic sinusitis: new algorithms for the optimization of treatment outcomes. In preparation

3) Testori T, Clauser T, Saibene AM, Artzi Z  Avila-Ortiz G, Chan HL, Chiapasco M., et al. Radiographic protrusion of dental implants in the maxillary sinus and nasal fossae: A multidisciplinary consensus utilizing the Modified Delphi Method. Int J Oral Implantol 2022: 15(3): 265-274 4) Testori T, Clauser T, Rapani A, Artzi Z, Avila-Ortiz G, Barootchi S, Bressan E, Chiapasco M., et al.  Indications for implant-supported rehabilitation of the posterior atrophic maxilla: A multidisciplinary consensus among experts in the field utilizing the Modified Delphi method.  Int J Oral Implantol 2024: 17(1): 89-100